Health and Population Minister Hatem el-Gabali, quoted by the state MENA news agency late on Wednesday, said the latest cases were a 16-year-old girl and an 8-year-old boy from two provinces north of Cairo.
The deadly H5N1 strain of the bird flu virus has so far killed two Egyptians.
"The girl and the boy were infected after coming into contact with domestic birds which had died, and tests ... confirmed they (the boy and girl) had been infected with bird flu," Gabali said, adding the two were in a stable condition.
The government says 11 Egyptians have now been infected by bird flu.
[...] Earlier on Wednesday, Egypt confirmed it's ninth case of human bird flu infection, in a girl aged 16 months from southern Egypt. On Sunday two sisters were confirmed to have the virus.
The avian flu virus has so far not been transmitted from human to human, but can be caught from infected birds.